The Transmissibility of Pellagra: Experimental Attempts at Transmission to the Human Subject

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By Joseph Goldbeeger, Surgeon, United States Public Health Service.

There is a very widely held belief, at least in the United States, that pellagra is a communicable disease. The evidence in support of this is almost wholly indirect and consists, in the main, of certain analogies to infectious diseases presented by some features of its epidemiology. When critically examined one finds that this evidence either completely falls or that it is susceptible of an entirely different interpretation. 2 The only direct evidence in favor of this view that

1 Read at the meeting of the Southern Medical Association, Atlanta, Ga., Nov. 16, 1916.

2 A discussion of the literature is reserved for a later communication. In the meantime the reader will find the following of interest: Goldberger, 1915, Vedder, 1916, and Voegtlln, 1914.

calls for serious consideration is the report by Harris (1913), of New Orleans, of a successful inoculation of a monkey with a nitrate from pellagrous lesions.

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